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CD95 Mouse, Unlabeled, Clone: 13, BD

Catalog No. BDB610197 Shop All BD Biosciences Products
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Catalog No. Quantity
BDB610197 50 μg
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Catalog No. BDB610197 Supplier BD Biosciences Supplier No. 610197

Description

Mouse Monoclonal Antibody

CD95 is a member of a family of cell surface receptors that includes tumor necrosis factor receptor (TNF-R), nerve growth factor receptor (NGF-R), CD40, CD27, CD30, and 4-1BB. Both murine and human Fas genes have been cloned and reportedly share 60% similarity in their amino acid sequences. CD95 (Fas) is a cell surface apoptosis-signaling molecule that is widely expressed in sites such as thymus, liver, heart, and ovary. Abnormalities in the Fas gene correlate with autoimmune features in mice and with unusually high levels of lymphocyte apoptosis in HIV-infected humans. Genetic studies have localized the Fas gene near the lpr (lymphoproliferation disease) locus on mouse chromosome 19 and further characterization reportedly has revealed that lpr is a mutation affecting the function of the Fas gene.

TRUSTED_SUSTAINABILITY

Specifications

Antigen CD95
Applications Western Blot
Classification Monoclonal
Clone 13
Concentration 250μg/mL
Conjugate Unconjugated
Description Fas, APO-1
Formulation Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Host Species Mouse
Immunogen Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Purification Method Affinity Purified
Quantity 50 μg
Regulatory Status RUO
Research Discipline Cell Biology
Primary or Secondary Primary
Target Species Canine, Chicken, Human, Mouse, Rat
Content And Storage Store undiluted at -20°C.
Isotype IgG2a κ
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For Research Use Only.

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