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Description
Reacts with a 45kD type I membrane molecule also known as APO-1, or Fas antigen. CD95 belongs to the tumor necrosis factor receptor (TNF-R) family of proteins and is expressed on various cells, including activated T cells and B cells. The interaction of CD95, Fas antigen, with Fas ligand is one of the many mechanisms that lead to apoptosis or programmed cell death. The interaction of CD95 expressing target cells with Fas ligand on cytotoxic T cells induces an apoptotic signal leading to target cell death. It has been reported that apoptosis is the
mechanism used by the immune system in clonal deletion of self-reactive T cells during embryological development.
Host Species: Mouse
Clone: EOS9.1
Isotype: IgM, κ
Species Reactivity: Human
Flow Cytometry, Functional Assay
Specifications
Specifications
| Antigen | CD95 |
| Applications | Flow Cytometry |
| Classification | Monoclonal |
| Clone | EOS9.1 |
| Concentration | 0.5mg/mL |
| Conjugate | Unconjugated |
| Description | Fas/APO-1 |
| Formulation | Aqueous buffered solution containing no preservative. |
| Host Species | Mouse |
| Purification Method | Affinity Purified |
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Safety and Handling
For Research Use Only.
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