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CD98 Mouse anti-Human, BB515, Clone: UM7F8, BD

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BDB565103 50 Tests
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Catalog No. BDB565103 Supplier BD Biosciences Supplier No. 565103

Item Discontinued This item has been discontinued by the supplier. Please to view product availability in your area.

Description

Mouse Monoclonal Antibody

CD98 is a disulfide-linked heterodimer composed of a ∽80-85 kDa, type II membrane glycoprotein heavy chain, (CD98hc), and ∽40-45 kDa light chain. The UM7F8 monoclonal antibody specifically recognizes CD98hc, which is also known as 4F2 heavy chain antigen (4F2hc). CD98 is broadly expressed on hematopoietic cells, including peripheral blood lymphocytes, monocytes and granulocytes (low), as well as non-hematopoietic cells, eg, intestinal epithelial cells. CD98 expression is upregulated on activated and proliferating cells. CD98hc is encoded by the SLC3A2 [solute carrier family 3 (amino acid transporter heavy chain), member 2] gene. CD98 reportedly functions in transmembrane amino acid transport and in the regulation of integrin signaling which are involved in the regulation of cellular activation, proliferation, and survival. The UM7F8 antibody is reportedly a functional antibody that can costimulate T cell proliferative responses.

TRUSTED_SUSTAINABILITY

Specifications

Antigen CD98
Applications Flow Cytometry
Classification Monoclonal
Clone UM7F8
Conjugate Brilliant Blue 515 (BB515)
Description SLC3A2; CD98HC; 4F2; 4F2hc; MDU1; NACAE; 4T2HC
Formulation Aqueous buffered solution containing ≤0.09% sodium azide
Host Species Mouse
Immunogen Human T-leukemic and Thymic Cell Lines
Purification Method Affinity Purified
Quantity 50 Tests
Regulatory Status RUO
Primary or Secondary Primary
Target Species Human
Content And Storage Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Isotype IgG1 κ
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