CDC25A, Rabbit, Monoclonal Antibody, Abnova™

Rabbit monoclonal antibody raised against a human CDC25A peptide using ARM Technology.

Supplier:  Abnova Corporation H00000993K

Catalog No. 89-205-539

Includes: Up to three rabbit IgG clones of 1mg each will be delivered to customer.

Description

CDC25A is a member of the CDC25 family of phosphatases. CDC25A is required for progression from G1 to the S phase of the cell cycle. It activates the cyclin-dependent kinase CDC2 by removing two phosphate groups. CDC25A is specifically degraded in response to DNA damage, which prevents cells with chromosomal abnormalities from progressing through cell division. CDC25A is an oncogene, although its exact role in oncogenesis has not been demonstrated. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq

Library Construction: Nonfusion antibody library from rabbit spleen (ARM Technology)
Expression: Overexpression vector and transfection into 293H cell line

Order Info

1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.

Specifications

• Antigen: CDC25A
• Classification: Monoclonal
• Conjugate: Unconjugated
• Formulation: In 1X PBS, pH 7.4
• Gene Accession No.: CDC25A
• Gene Symbols: CDC25A
• Immunogen: A synthetic peptide of human CDC25A
• Regulatory Status: RUO
• Gene ID (Entrez): 993
• Content And Storage: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
• Isotype: IgG

• Applications: ELISA, Western Blot
• Concentration: 1mg
• Description: cell division cycle 25 homolog A (S. pombe)
• Gene: CDC25A
• Gene Alias: CDC25A2
• Host Species: Rabbit
• Quantity: 1 mg x up to 3 Abs
• Primary or Secondary: Primary
• Target Species: Human
• Form: Liquid