Learn More
Description
Cyclin-dependent kinases can be activated by CDC25, which removes inhibitory phosphates from tyrosine and threonine residues. At least three CDC25 genes (CDC25A, CDC25B, and CDC25C) have been identified in humans. Whereas CDC25A and CDC25B are expressed throughout the cell cycle, with peak expression in G1 for CDC25A and in both G1-S-phase and G2 for CDC25B, CDC25C is predominantly expressed in G2.
Host Species: Mouse
Clone: 25C07 (TC-113)
Isotype: IgG1/κ
Cross Reactivity: Human. Does not react with mouse and rat. Others-not tested.
Epitope: aa222-246
Immunogen: Recombinant human CDC25C protein.
Molecular Weight: 53-56kDa
Positive Control: HeLa, HT29, or LS174T cells. Breast CA.
Cellular Localization: Cytoplasmic
Ab-7 is excellent for the staining of formalin-fixed, paraffin-embedded tissues.
Immunofluorescence, Immunohistochemistry (Formalin/Paraffin), Immunoprecipitation, Western Blotting
Abbreviations: AP=Affinity Purification, ChIP=Chromatin IP, CM=Confocal Microscopy, DB=Dot Blot, EIA=ELISA, EM=Electron Microscopy, FC=Flow Cytometry, GS=Gel Supershift, IC=Immunocytochemistry, IF=Immunofluorescence, IH=Immunohistology/Immunohistochemistry, IP=Immunoprecipitation, IPK=IP Kinase Assay, KA=Kinase Assay, NEUT=Neutralization, PIA=Peptide Inhibition Assay, RIA=Radioimmunossay, TCA=T Cell Activation, WB=Western Blotting, Species: Am=Amphibian, Av=Avian, B=Bovine, Ca=Cat ,Ck=Chicken, D=Dog, Dr=Deer, Ds=Drosophila, El=Elk, Fg=Frog, Fs=Fish, Ft=Ferret, G=Goat, Gp=Guinea Pig, H=Horse, Hm=Hamster, Hu=Human, K=Kangaroo, Ms=Mouse, Nhp=Non-Human Primate, O=Ovine, P=Porcine, Rb=Rabbit, Rp=Reptile, Rt=Rat, Ys=Yeast, Xn=Xenopus, (wk)=cross reacts weakly
Specifications
Specifications
| Antigen | CDC25C Ab-7 |
| Classification | Monoclonal |
| Concentration | 1mg/mL |
| Conjugate | Unconjugated |
| Host Species | Mouse |
| Immunogen | Recombinant human CDC25C protein. |
| Quantity | 200 μL |
| Primary or Secondary | Primary |
| Target Species | Human |
| Form | Purified |
| Show More |
By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.