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anti-Cdk7/ p40MO15/CAK Ab-1, Clone: MO-1.1, Epredia™ LabVision

Catalog No. MS219PABX Shop All Epredia Products
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MS219PABX 200 μL
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Description

Mouse Monoclonal Antibody

CDK7 is cdk activating kinase associated with the 34kDa cyclin H protein, and a 36kDa unnamed protein. CDK7/cyclin H is an integral part of the general transcription factor complex TFIIH; hence is important for activated transcription of polymerase II-dependent promoters and DNA repair. CDK7 is nuclear at all stages of the cell division cycle, except for mitosis indicating that its activity is required for key CDKs operating in distinct cell cycle phases.

Host Species: Mouse
Clone: MO-1.1
Isotype: IgG2b
Cross Reactivity: Human and Rat. Does not react with mouse. Others-not known.
Epitope: 221 amino acid fragment of C-terminus
Immunogen: A recombinant 221 amino acid fragment of the C-terminus human p40MO15 protein.
Molecular Weight: 40kDa
Positive Control: HT29 and LS174T cells
Cellular Localization: Nuclear and cytoplasmic

Ab-1 is well suited for multiple biochemical applications including immunoprecipitation of kinase activity

Flow Cytometry, Immunofluorescence, Immunohistochemistry (Frozen), Immunoprecipitation, Kinase Assay, Western Blotting

Abbreviations: AP=Affinity Purification, ChIP=Chromatin IP, CM=Confocal Microscopy, DB=Dot Blot, EIA=ELISA, EM=Electron Microscopy, FC=Flow Cytometry, GS=Gel Supershift, IC=Immunocytochemistry, IF=Immunofluorescence, IH=Immunohistology/Immunohistochemistry, IP=Immunoprecipitation, IPK=IP Kinase Assay, KA=Kinase Assay, NEUT=Neutralization, PIA=Peptide Inhibition Assay, RIA=Radioimmunossay, TCA=T Cell Activation, WB=Western Blotting, Species: Am=Amphibian, Av=Avian, B=Bovine, Ca=Cat ,Ck=Chicken, D=Dog, Dr=Deer, Ds=Drosophila, El=Elk, Fg=Frog, Fs=Fish, Ft=Ferret, G=Goat, Gp=Guinea Pig, H=Horse, Hm=Hamster, Hu=Human, K=Kangaroo, Ms=Mouse, Nhp=Non-Human Primate, O=Ovine, P=Porcine, Rb=Rabbit, Rp=Reptile, Rt=Rat, Ys=Yeast, Xn=Xenopus, (wk)=cross reacts weakly

Specifications

Antigen Cdk7/ p40MO15/CAK Ab-1
Concentration 1mg/mL
Host Species Mouse
Immunogen A recombinant 221 amino acid fragment of the C-terminus human p40MO15 protein.
Quantity 200 μL
Primary or Secondary Primary
Target Species Human, Rat
Form Purified
Isotype IgG2b
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