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CDw210 Rat anti-Human, Unlabeled, Clone: 3F9, BD

Catalog No. BDB556012 Shop All BD Biosciences Products
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BDB556012 0.1 mg
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Catalog No. BDB556012 Supplier BD Biosciences Supplier No. 556012
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Description

Rat Monoclonal Antibody

Reaacts with 90-110kDa protein expressed on T cells, B cells, NK cells, and monocyte/macrophages. It belongs to the class II cytokine receptor family which includes IFNγR (CDw119), IFNα/βR (CD118) and tissue factor (CD142). IL-10R has been found to play a role in signal transduction by activating specific STAT proteins (STAT3 and STAT1) and inducing gene transcription. Other reports indicate that IL-10 protein binding to NK cells appears to be stimulatory, in contrast to its binding to T cells and monocytes/macrophages. Clone 3F9 is specific for human IL-10R and its binding to the receptor can be blocked by recombinant human IL-10 (rhIL-10). This antibody is routinely tested by flow cytometric analysis. Other applications were tested at BD Biosciences Pharmingen during antibody development only or reported in the literature.

TRUSTED_SUSTAINABILITY

Specifications

Antigen CDw210
Applications Flow Cytometry
Classification Monoclonal
Clone 3F9
Concentration 0.5mg/mL
Conjugate Unconjugated
Description IL-10 receptor
Formulation Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species Rat
Immunogen Human IL-10R alpha Recombinant Protein
Purification Method Affinity Purified
Quantity 0.1 mg
Regulatory Status RUO
Research Discipline Cell Biology
Primary or Secondary Primary
Target Species Human
Content And Storage Store undiluted at 4°C
Isotype IgG2a κ
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For Research Use Only.

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