CEACAM Pan Mouse anti-Human, Clone: D14HD11, Invitrogen™
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA117761
This antibody recognizes native human CEACAM1, 3, 4, 5, 6 protein expressed in transfected mammalian cells.CEA-related cell adhesion molecules (CEACAM) belong to the carcinoembryonic antigen (CEA) family. The CEA family proteins belong to the immuno-globulin (Ig) superfamily and are composed of one Ig variable-like (IgV) and a varying number (0-6) of Ig constant-like (IgC) domains. CEACAM molecules are membrane-bound either via a transmembrane domain or a glycosyl phosphatidyl inositol (GPI) anchor. CEACAM molecules are differentially expressed in epithelial cells or in leucocytes. Over-expression of CEA/CEACAM5 in tumors of epithelial origin is the basis of its wide-spread use as a tumor marker. The function of CEACAM family members varies widely: they function as cell adhesion molecules, tumor suppressors, regulators of lymphocyte and dendritic cell activation, receptors of Neisseria species and other bacteria.
|PBS with no preservative; pH 7.2|
|O75871, P06731, P13688, P40198, P40199|
|pan CEACAM, Carcinoembryonic antigen-related cell adhesion molecule 1, BGP, BGP-1, CD66a, Biliary glycoprotein 1, Carcinoembryonic antigen-related cell adhesion molecule 3, CD66d, Carcinoembryonic antigen CGM1, CGM1, Carcinoembryonic antigen-related cell adhesion molecule 4, Carcinoembryonic antigen CGM7, CGM7, Non-specific cross-reacting antigen W236, Carcinoembryonic antigen-related cell adhesion molecule 5, CEA, CD66e, Carcinoembryonic antigen-related cell adhesion molecule 6, CD66c, NCA|
|Store at 4°C short term. For long term storage, Store at -20°C, avoiding freeze/thaw cycles.|
|1048, 1084, 1089, 4680, 634|
|ELISA, Flow Cytometry, Immunocytochemistry, Immunofluorescence, Western Blot|
|CEACAM1, CEACAM3, CEACAM4, CEACAM5, CEACAM6|
|Immunization with extracted proteins of CEACAM5.|
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