CD66 (CEACAM) Monoclonal Antibody (D14HD11), Invitrogen™

Mouse Monoclonal Antibody

Supplier:  Thermo Scientific MA117761

Catalog No. 01-670-174

Description

This antibody recognizes native human CEACAM1, 3, 4, 5, 6 protein expressed in transfected mammalian cells.

The CD66 molecules are 180-200 kDa glycoproteins of carcinoembryonic antigen family. They are present on all blood granulocytes and some tissue macrophages, but are absent from other hematopoietic cells. The expression of CD66 increases significantly on granulocytes upon their activation. CD66a (BGP1, CEACAM1) and CD66d (CGM1, CEACAM3), as well as CEACAM2 and 4, are transmembrane proteins, whereas CD66c (CEAL, NCA, CEACAM6) and CD66e (CEA, CEACAM5), as well as CEACAM7 and 8, are anchored to the plasma membrane by C-terminal glycosylphosphatidylinositol (GPI) lipid moiety.

Specifications

• Antigen: CD66 (CEACAM)
• Classification: Monoclonal
• Concentration: 2 mg/mL
• Formulation: PBS with no preservative; pH 7.2
• Gene Accession No.: O75871, P06731, P13688, P40198, P40199
• Gene Symbols: CEACAM1, CEACAM3, CEACAM4, CEACAM5, CEACAM6
• Immunogen: Immunization with extracted proteins of CEACAM5.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: ELISA, Flow Cytometry, Immunocytochemistry, Western Blot
• Clone: D14HD11
• Conjugate: Unconjugated
• Gene: CEACAM6
• Gene Alias: antigen CD66; BGP; BGP1; BGP-1; BGPI; Biliary glycoprotein 1; Carcinoembryonic antigen; Carcinoembryonic antigen CGM1; carcinoembryonic antigen CGM7; carcinoembryonic antigen gene family member 1; carcinoembryonic antigen gene family member 7; carcinoembryonic antigen related cell adhesion molecule 1; carcinoembryonic antigen related cell adhesion molecule 3; carcinoembryonic antigen related cell adhesion molecule 4; carcinoembryonic antigen related cell adhesion molecule 5; carcinoembryonic antigen related cell adhesion molecule 6; carcinoembryonic antigen-related cell adhesion molecule 1; carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein); carcinoembryonic antigen-related cell adhesion molecule 3; Carcinoembryonic antigen-related cell adhesion molecule 4; carcinoembryonic antigen-related cell adhesion molecule 4-sv1; carcinoembryonic antigen-related cell adhesion molecule 4-sv2; carcinoembryonic antigen-related cell adhesion molecule 5; Carcinoembryonic antigen-related cell adhesion molecule 6; carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen); CD66a; CD66a antigen; CD66c; CD66d; CD66d antigen; CD66e; CEA; CEACAM1; CEACAM-1; CEACAM3; CEACAM-3; CEACAM4; CEACAM5; CEACAM-5; CEACAM6; CEACAM-6; CEAL; CGM1; CGM7; CGM7_HUMAN; Cluster of Differentiation 66c; meconium antigen 100; NCA; Non-specific crossreacting antigen; nonspecific cross-reacting antigen; Nonspecific cross-reacting antigen (NCA); non-specific cross-reacting antigen W236; nonspecific cross-reacting antigen W236; normal cross-reacting antigen; pan CEACAM; W264; W282
• Host Species: Mouse
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 1048, 1084, 1089, 4680, 634
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid