CHIT1, Rabbit, Monoclonal Antibody, Abnova™

Rabbit monoclonal antibody raised against a human CHIT1 peptide using ARM Technology.

Supplier:  Abnova Corporation H00001118K

Catalog No. 89-205-570

Includes: Up to three rabbit IgG clones of 1mg each will be delivered to customer.

Description

Chitotriosidase is secreted by activated human macrophages and is markedly elevated in plasma of Gaucher disease patients. The expression of chitotriosidase occurs only at a late stage of differentiation of monocytes to activated macrophages in culture. Human macrophages can synthesize a functional chitotriosidase, a highly conserved enzyme with a strongly regulated expression. This enzyme may play a role in the degradation of chitin-containing pathogens. [provided by RefSeq

Library Construction: Nonfusion antibody library from rabbit spleen (ARM Technology)
Expression: Overexpression vector and transfection into 293H cell line

Order Info

1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.

Specifications

• Antigen: CHIT1
• Classification: Monoclonal
• Conjugate: Unconjugated
• Formulation: In 1X PBS, pH 7.4
• Gene Accession No.: CHIT1
• Gene Symbols: CHIT1
• Immunogen: A synthetic peptide of human CHIT1
• Regulatory Status: RUO
• Gene ID (Entrez): 1118
• Content And Storage: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
• Isotype: IgG

• Applications: ELISA, Western Blot
• Concentration: 1mg
• Description: chitinase 1 (chitotriosidase)
• Gene: CHIT1
• Gene Alias: CHI3, CHIT, FLJ00314, MGC125322
• Host Species: Rabbit
• Quantity: 1 mg x up to 3 Abs
• Primary or Secondary: Primary
• Target Species: Human
• Form: Liquid