CHMP6, Rabbit, Monoclonal Antibody, Abnova™

Rabbit monoclonal antibody raised against a human CHMP6 peptide using ARM Technology.

Supplier:  Abnova Corporation H00079643K

Catalog No. 89-206-760

Includes: Up to three rabbit IgG clones of 1mg each will be delivered to customer.

Description

CHMP6 belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. These proteins are components of ESCRT-III (endosomal sorting complex required for transport III), a complex involved in degradation of surface receptor proteins and formation of endocytic multivesicular bodies (MVBs). Some CHMPs have both nuclear and cytoplasmic/vesicular distributions, and one such CHMP, CHMP1A (MIM 164010), is required for both MVB formation and regulation of cell cycle progression (Tsang et al., 2006 [PubMed 16730941]).[supplied by OMIM

Library Construction: Nonfusion antibody library from rabbit spleen (ARM Technology)
Expression: Overexpression vector and transfection into 293H cell line

Order Info

1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.

Specifications

• Antigen: CHMP6
• Classification: Monoclonal
• Conjugate: Unconjugated
• Formulation: In 1X PBS, pH 7.4
• Gene Accession No.: CHMP6
• Gene Symbols: CHMP6
• Immunogen: A synthetic peptide of human CHMP6
• Regulatory Status: RUO
• Gene ID (Entrez): 79643
• Content And Storage: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
• Isotype: IgG

• Applications: ELISA, Western Blot
• Concentration: 1mg
• Description: chromatin modifying protein 6
• Gene: CHMP6
• Gene Alias: FLJ11749, VPS20
• Host Species: Rabbit
• Quantity: 1 mg x up to 3 Abs
• Primary or Secondary: Primary
• Target Species: Human
• Form: Liquid