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Cholera Toxin beta Rabbit anti-Bacteria, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA125635

Catalog No. PA125635


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Description

Description

PA1-25635 detects Cholera toxin from bacteria samples. PA1-25635 has been successfully used in immunohistochemistry and ELISA procedures. The PA1-25635 immunogen is purified Choleragenoid. Store at 4°C short term. For extended storage aliquot and store at -20°C or below. Avoid freeze-thaw cycles.

Cholera toxin (sometimes abbreviated to CTX, Ctx, or CT) is a protein complex secreted by the bacterium Vibrio cholerae. CTX is the causative agent of cholera infection. The alpha subunit contains two chains, A1 and A2, linked by a disulfide bridge. The alpha subunit activates the adenylate cyclase enzyme in cells of the intestinal mucosa leading to increased levels of intracellular cAMP. The beta subunit of cholera toxin binds to a GM1-ganglioside receptor which is widely accepted to initiate toxin action by triggering uptake and delivery of the toxin alpha subunit into cells. The holotoxin consists of a pentameric ring of beta subunits whose central pore is occupied by the alpha subunit.
Specifications

Specifications

Cholera Toxin beta
Polyclonal
Unconjugated
Liquid
Rabbit
IgG
500 μL
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
Bacteria
ELISA, Immunohistochemistry
4 mg/mL
PBS with 0.1% sodium azide; pH 7.2
beta subunit cholera toxin; CTB; VC1456; CTX
Purified Choleragenoid.
IgG fraction
RUO
Antibody
Polyclonal
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