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Description
CLA-1 (CD36 and LIMPII Analogous-1) is member of a novel gene family that includes CD36, LIMPII, and SR-BI. CD36 is a cell surface glycoprotein that binds to collagen type I and thrombospondin. LIMPII (lysosomal integral membrane protein II), as its name suggests, is expressed on the membrane of lysosomes. SR-BI (scavenger receptor type B class I) is involved in the selective uptake of cholesterol esters. These proteins include two membrane-anchoring regions, two short cytoplasmic tails, and a large extracellular/luminal domain. CLA-1 mRNA is detected in a wide range of tissues including adrenal glands, liver, and testis. Its expression and similarity with other family members suggest it may play a role in HDL metabolism. However, identification of the CLA-1 receptor on monocytes indicates additional CLA-1 functions in leukocytes.
Immunofluorescence, Western Blotting
Specifications
Specifications
| Antigen | CLA-1 |
| Applications | Western Blot |
| Classification | Monoclonal |
| Clone | 25 |
| Concentration | 250μg/mL |
| Conjugate | Unconjugated |
| Description | CD36 and LIMPII Analogous-1 |
| Formulation | Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide. |
| Host Species | Mouse |
| Immunogen | Human CLA-1 aa. 104-294 |
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Safety and Handling
For Research Use Only.
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