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Clec12A Rat anti-Mouse, Brilliant Violet 421, Clone: 5D3 (also known as 1/06-5D3), BD

Rat Monoclonal Antibody

Manufacturer:  BD Biosciences 564795

Catalog No. BDB564795


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Description

Description

The 5D3 monoclonal antibody specifically binds to mouse C-type lectin domain family 12 member A (Clec12A), also known as myeloid inhibitory C-type lectin-like receptor (MICL), C-type lectine-like molecule 1 (CLL-1) or Dendritic cell-associated lectin 2 (DCAL-2). Clec12A is expressed on plasmacytoid dendritic cells, subsets of myeloid dendritic cells, monocytes, macrophage and B cells. Clec12A has one single C-type lectin-like domain and one cytoplasmic immunoreceptor tyrosine-based inhibitory motif. Clec12A reportedly serves as a negative regulator of granulocyte and monocyte function.

The antibody was conjugated to BD Horizon BV421 which is part of the BD Horizon Brilliant™ Violet family of dyes. With an Ex Max of 407-nm and Em Max at 421-nm, BD Horizon BV421 can be excited by the violet laser and detected in the standard Pacific Blue™ filter set (eg, 450/50-nm filter). BD Horizon BV421 conjugates are very bright, often exhibiting a 10 fold improvement in brightness compared to Pacific Blue conjugates.

Specifications

Specifications

Clec12A
5D3 (also known as 1/06-5D3)
Brilliant Violet 421
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Rat
IgG2a, κ
50μg
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Monoclonal
Flow Cytometry
0.2mg/mL
CL12A; C-type lectin domain family 12 member A; CLL-1; DCAL-2; KLRL1; MICL
Affinity Purified
Mouse Clec12A Transfected Cell Line
The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
RUO
Primary
Murine
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