Clec12A Rat anti-Mouse, Brilliant Violet 421, Clone: 5D3 (also known as 1/06-5D3), BD
Rat Monoclonal Antibody
Manufacturer: BD Biosciences 564795
The 5D3 monoclonal antibody specifically binds to mouse C-type lectin domain family 12 member A (Clec12A), also known as myeloid inhibitory C-type lectin-like receptor (MICL), C-type lectine-like molecule 1 (CLL-1) or Dendritic cell-associated lectin 2 (DCAL-2). Clec12A is expressed on plasmacytoid dendritic cells, subsets of myeloid dendritic cells, monocytes, macrophage and B cells. Clec12A has one single C-type lectin-like domain and one cytoplasmic immunoreceptor tyrosine-based inhibitory motif. Clec12A reportedly serves as a negative regulator of granulocyte and monocyte function.
The antibody was conjugated to BD Horizon BV421 which is part of the BD Horizon Brilliant Violet family of dyes. With an Ex Max of 407-nm and Em Max at 421-nm, BD Horizon BV421 can be excited by the violet laser and detected in the standard Pacific Blue filter set (eg, 450/50-nm filter). BD Horizon BV421 conjugates are very bright, often exhibiting a 10 fold improvement in brightness compared to Pacific Blue conjugates.
|5D3 (also known as 1/06-5D3)|
|Brilliant Violet 421|
|Aqueous buffered solution containing BSA and ≤0.09% sodium azide.|
|Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.|
|CL12A; C-type lectin domain family 12 member A; CLL-1; DCAL-2; KLRL1; MICL|
|Mouse Clec12A Transfected Cell Line|
|The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.|
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