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Clec12A Rat anti-Mouse, Brilliant Violet 421, Clone: 5D3 (also known as 1/06-5D3), BD
Rat Monoclonal Antibody
Supplier: BD Biosciences 564795
Description
The 5D3 monoclonal antibody specifically binds to mouse C-type lectin domain family 12 member A (Clec12A), also known as myeloid inhibitory C-type lectin-like receptor (MICL), C-type lectine-like molecule 1 (CLL-1) or Dendritic cell-associated lectin 2 (DCAL-2). Clec12A is expressed on plasmacytoid dendritic cells, subsets of myeloid dendritic cells, monocytes, macrophage and B cells. Clec12A has one single C-type lectin-like domain and one cytoplasmic immunoreceptor tyrosine-based inhibitory motif. Clec12A reportedly serves as a negative regulator of granulocyte and monocyte function.
The antibody was conjugated to BD Horizon BV421 which is part of the BD Horizon Brilliant™ Violet family of dyes. With an Ex Max of 407-nm and Em Max at 421-nm, BD Horizon BV421 can be excited by the violet laser and detected in the standard Pacific Blue™ filter set (eg, 450/50-nm filter). BD Horizon BV421 conjugates are very bright, often exhibiting a 10 fold improvement in brightness compared to Pacific Blue conjugates.
Specifications
Clec12A | |
Monoclonal | |
0.2mg/mL | |
CL12A; C-type lectin domain family 12 member A; CLL-1; DCAL-2; KLRL1; MICL | |
Rat | |
Affinity Purified | |
RUO | |
Mouse | |
IgG2a κ |
Flow Cytometry | |
5D3 (also known as 1/06-5D3) | |
Brilliant Violet 421 | |
Aqueous buffered solution containing BSA and ≤0.09% sodium azide. | |
Mouse Clec12A Transfected Cell Line | |
50 μg | |
Primary | |
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. |
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