Clec9A Rat anti-Mouse, Alexa Fluor 647, Clone: 10B4, BD

Rat Monoclonal Antibody

Supplier:  BD Biosciences 564272

Catalog No. BDB564272

Description

The 10B4 monoclonal antibody specifically binds to mouse Clec9A. Mouse Clec9A (C-type lectin domain family member 9A) is also known as DNGR1 (Dendritic cell natural killer lectin group receptor 1). It is a type II membrane protein with a single extracellular C-type lectin domain. Clec9A is a dendritic cell subtype-restricted C-type lectin-like receptor. Clec9A is selectively expressed on plasmacytoid dendritic cells and CD8+ myeloid dendritic cells. Clec9A reportedly serves as a receptor for necrotic cells. It can mediate the cross-presentation of dead-cell associated antigens in a Syk-dependent manner.

Specifications

• Antigen: Clec9A
• Classification: Monoclonal
• Concentration: 0.2mg/mL
• Description: CLC9A; Clec9a; DNGR-1; C-type lectin domain family 9 member A
• Host Species: Rat
• Purification Method: Affinity Purified
• Regulatory Status: RUO
• Target Species: Mouse
• Isotype: IgG2a κ

• Applications: Flow Cytometry
• Clone: 10B4
• Conjugate: Alexa Fluor 647
• Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
• Immunogen: Mouse Clec9A Peptide
• Quantity: 50 μg
• Primary or Secondary: Primary
• Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.