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Clec9A Rat anti-Mouse, Alexa Fluor 647, Clone: 10B4, BD

Rat Monoclonal Antibody

Manufacturer:  BD Biosciences 564272

Catalog No. BDB564272


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Description

Description

The 10B4 monoclonal antibody specifically binds to mouse Clec9A. Mouse Clec9A (C-type lectin domain family member 9A) is also known as DNGR1 (Dendritic cell natural killer lectin group receptor 1). It is a type II membrane protein with a single extracellular C-type lectin domain. Clec9A is a dendritic cell subtype-restricted C-type lectin-like receptor. Clec9A is selectively expressed on plasmacytoid dendritic cells and CD8+ myeloid dendritic cells. Clec9A reportedly serves as a receptor for necrotic cells. It can mediate the cross-presentation of dead-cell associated antigens in a Syk-dependent manner.

Specifications

Specifications

Clec9A
10B4
Alexa Fluor 647
Aqueous buffered solution containing ≤0.09% sodium azide.
Rat
IgG2a, κ
RUO
Primary
Murine
Flow Cytometry
0.2mg/mL
CLC9A; Clec9a; DNGR-1; C-type lectin domain family 9 member A
Affinity Purified
Mouse Clec9A Peptide
50μg
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Monoclonal
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