Clec9A Rat anti-Human, Brilliant Violet 421, Clone: 3A4/Clec9A, BD

Rat Monoclonal Antibody

Supplier:  BD Biosciences 564266

Catalog No. BDB564266

Description

The 3A4/Clec9A monoclonal antibody specifically binds to human Clec9A (C-type lectin domain family member 9A). Clec9A is a type II transmembrane glycoprotein with a single extracellular C-type lectin domain. Clec9A is also known as CD370 and DNGR1 (Dendritic cell natural killer lectin group receptor 1). Clec9A is selectively expressed on CD141+ myeloid dendritic cells. Clec9A reportedly functions as an endocytic receptor for necrotic cells. It can mediate the cross-presentation of dead-cell associated antigens by dendritic cells in a Syk-dependent manner. The 3A4 antibody reportedly crossreacts with peripheral blood dendritic cells form Pigtail macaques ( Macaca nemestrina ).

Specifications

• Antigen: Clec9A
• Classification: Monoclonal
• Concentration: 0.2mg/mL
• Description: CD370; C-type lectin domain family 9 member A; CLEC9A; DNGR1
• Host Species: Rat
• Purification Method: Affinity Purified
• Regulatory Status: RUO
• Target Species: Human
• Isotype: IgG2a κ

• Applications: Flow Cytometry
• Clone: 3A4/Clec9A
• Conjugate: Brilliant Violet 421
• Formulation: Aqueous buffered solution containing BSA and ≤0.09% sodium azide
• Immunogen: Human Clec9A Peptide
• Quantity: 25 μg
• Primary or Secondary: Primary
• Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.