colipase, pancreatic, Mouse, Polyclonal Antibody, Abnova
Mouse polyclonal antibody raised against a full-length human CLPS protein.
Manufacturer: Abnova Corporation H00001208B01
The protein encoded by this gene is a cofactor needed by pancreatic lipase for efficient dietary lipid hydrolysis. It binds to the C-terminal, noncatalytic domain of lipase, thereby stabilizing an active conformation and considerably increasing the overall hydrophobic binding site. The gene product allows lipase to anchor noncovalently to the surface of lipid micelles, counteracting the destabilizing influence of intestinal bile salts. This cofactor is only expressed in pancreatic acinar cells, suggesting regulation of expression by tissue-specific elements. [provided by RefSeqSequence: MEKILILLLVALSVAYAAPGPRGIIINLENGELCMNSAQCKSNCCQHSSALGLARCTSMASENSECSVKTLYGIYYKCPCERGLTCEGDKTIVGSITNTNFGICHDAGRSKQ
|CLPS (NP_001823.1, 1 a.a. ~ 112 a.a) full-length human protein.|
|Mouse polyclonal antibody raised against a full-length human CLPS protein.|
|Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.|
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