Learn More
Description
The protein encoded by this gene is a polypeptide hormone whose actions appear to be restricted to the nervous system where it promotes neurotransmitter synthesis and neurite outgrowth in certain neuronal populations. The protein is a potent survival factor for neurons and oligodendrocytes and may be relevant in reducing tissue destruction during inflammatory attacks. A mutation in this gene, which results in aberrant splicing, leads to ciliary neurotrophic factor deficiency, but this phenotype is not causally related to neurologic disease. A read-through transcript variant composed of ZFP91 and CNTF sequence has been identified, but it is thought to be noncoding. Read-through transcription of ZFP91 and CNTF has also been observed in mouse. [provided by RefSeq
Specifications
Specifications
| Antigen | CNTF |
| Applications | Immunoprecipitation, Western Blot |
| Classification | Polyclonal |
| Conjugate | Unconjugated |
| Description | Rabbit polyclonal antibody raised against a full-length human CNTF protein. |
| Formulation | No additive |
| Gene | CNTF |
| Gene Accession No. | NM_000614 |
| Gene Alias | HCNTF |
| Gene Symbols | CNTF |
| Show More |
By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.