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ciliary neurotrophic factor, Rabbit, Purified MaxPab™ Polyclonal Antibody, Abnova™

Catalog No. 89017530 Shop All Abnova Corporation Products
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89-017-530 100 μg
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Catalog No. 89-017-530 Supplier Abnova Corporation Supplier No. H00001270D01P
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Description

Rabbit polyclonal antibody raised against a full-length human CNTF protein.

The protein encoded by this gene is a polypeptide hormone whose actions appear to be restricted to the nervous system where it promotes neurotransmitter synthesis and neurite outgrowth in certain neuronal populations. The protein is a potent survival factor for neurons and oligodendrocytes and may be relevant in reducing tissue destruction during inflammatory attacks. A mutation in this gene, which results in aberrant splicing, leads to ciliary neurotrophic factor deficiency, but this phenotype is not causally related to neurologic disease. A read-through transcript variant composed of ZFP91 and CNTF sequence has been identified, but it is thought to be noncoding. Read-through transcription of ZFP91 and CNTF has also been observed in mouse. [provided by RefSeq

Sequence: MAFTEHSPLTPHRRDLCSRSIWLARKIRSDLTALTESYVKHQGLNKNINLDSADGMPVASTDQWSELTEAERLQENLQAYRTFHVLLARLLEDQQVHFTPTEGDFHQAIHTLLLQVAAFAYQIEELMILLEYKIPRNEADGMPINVGDGGLFEKKLWGLKVLQELSQWTVRSIHDLRFISSHQTGIPARGSHYIANNKKM

Specifications

Antigen ciliary neurotrophic factor
Applications Western Blot
Classification Polyclonal
Conjugate Unconjugated
Description Rabbit polyclonal antibody raised against a full-length human CNTF protein.
Formulation PBS with no preservative; pH 7.4
Gene CNTF
Gene Accession No. NM_000614
Gene Alias HCNTF
Gene Symbols CNTF
Host Species Rabbit
Immunogen CNTF (NP_000605.1, 1 a.a. ∼ 200 a.a) full-length human protein.
Purification Method Affinity Purified
Quantity 100 μg
Regulatory Status RUO
Research Discipline Neurobiology
Primary or Secondary Primary
Gene ID (Entrez) 1270
Target Species Human
Content And Storage Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Product Type Antibody
Isotype IgG
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