COL17A1 Rabbit anti-Human, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA526108
DescriptionCOL17A1 is the alpha chain of type XVII collagen. Unlike most collagens, collagen XVII is a transmembrane protein, and a structural component of hemidesmosomes, multiprotein complexes at the dermal-epidermal basement membrane zone that mediate adhesion of keratinocytes to the underlying membrane. COL17A1 is a member of the FACIT collagen family (fibril-associated collagens with interrupted helices). Moreover, COL17A1 is localized to tissues containing type I collagen so, like other members of this collagen family, it may serve to maintain the integrity of the extracellular matrix. Diseases associated with COL17A1 dysfunction include epithelial recurrent erosion dystrophy and epidermolysis bullosa.
|PBS with 0.09% sodium azide|
|BA16H23.2, BP180, BPA-2, BPAG2, LAD-1, 180 kDa bullous pemphigoid antigen 2, alpha 1 type XVII collagen, bA16H23.2 (collagen, type XVII, alpha 1 (BP180)), bullous pemphigoid antigen 2 (180kD), collagen XVII, alpha-1 polypeptide, collagen alpha-1(XVII) chain|
|-20° C, Avoid Freeze/Thaw Cycles|
|Flow Cytometry, Western Blot|
|KLH conjugated synthetic peptide between 475-504 amino acids from the central region of human COL17A1|
|Antigen Affinity Chromatography, Protein A|
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