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COL1A1, Rabbit, Monoclonal Antibody, Abnova™

Rabbit monoclonal antibody raised against a human COL1A1 peptide using ARM Technology.

Supplier:  Abnova Corporation H00001277K

Catalog No. 89-205-456


Includes: Up to three rabbit IgG clones of 1mg each will be delivered to customer.

Description

Description

This gene encodes the pro-alpha1 chains of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon. Mutations in this gene are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIA, Ehlers-Danlos syndrome Classical type, Caffey Disease and idiopathic osteoporosis. Reciprocal translocations between chromosomes 17 and 22, where this gene and the gene for platelet-derived growth factor beta are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans, resulting from unregulated expression of the growth factor. Two transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene. [provided by R. Dalgleish

Library Construction: Nonfusion antibody library from rabbit spleen (ARM Technology)
Expression: Overexpression vector and transfection into 293H cell line

Order Info

  1. Customer may provide cell or tissue lysate for antibody screening.
  2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.

Specifications

Specifications

COL1A1
Monoclonal
Unconjugated
In 1X PBS, pH 7.4
COL1A1
COL1A1
A synthetic peptide of human COL1A1
RUO
1277
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
IgG
ELISA, Western Blot
1mg
collagen, type I, alpha 1
COL1A1
OI4
Rabbit
1 mg x up to 3 Abs
Primary
Human
Liquid
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