COX7A2L (B01P), Mouse anti-Human, Purified MaxPab Polyclonal Antibody, Abnova
Mouse polyclonal antibody raised against a full-length human COX7A2L protein.
Manufacturer: Abnova Corporation H00009167B01P
Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes a protein similar to polypeptides 1 and 2 of subunit VIIa in the C-terminal region, and also highly similar to the mouse Sig81 protein sequence. This gene is expressed in all tissues, and upregulated in a breast cancer cell line after estrogen treatment. It is possible that this gene represents a regulatory subunit of COX and mediates the higher level of energy production in target cells by estrogen. [provided by RefSeqSequence: MYYKFSGFTQKLAGAWASEAYSPQGLKPVVSTEAPPIIFATPTKLTSDSTVYDYAGKNKVPELQKFFQKADGVPVYLKRGLPDQMLYRTTMALTVGGTIYCLIALYMASQPKNK
|In 1X PBS, pH 7.4|
|Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.|
|Mouse polyclonal antibody raised against a full-length human COX7A2L protein.|
|COX7A2L (AAH05251, 1 a.a. ~ 114 a.a) full-length human protein.|
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