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cAMP responsive element binding protein-like 2, Mouse, Polyclonal Antibody, Abnova™

Mouse polyclonal antibody raised against a full-length human CREBL2 protein.

Manufacturer:  Abnova Corporation H00001389B01

Catalog No. 89-005-171


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Description

Description

cAMP response element (CRE)-binding protein-like-2 (CREBL2) was identified in a search to find genes in a commonly deleted region on chromosome 12p13 flanked by ETV6 and CDKN1B genes, frequently associated with hematopoietic malignancies, as well as breast, nonsmall-cell lung and ovarian cancers. CREBL2 shares a 41% identity with CRE-binding protein (CREB) over a 48-base long region which encodes the bZip domain of CREB. The bZip domain consists of about 30 amino acids rich in basic residues involved in DNA binding, followed by a leucine zipper motif involved in protein dimerization. This suggests that CREBL2 encodes a protein with DNA binding capabilities. The occurance of CREBL2 deletion in malignancy suggests that CREBL2 may act as a tumor suppressor gene. [provided by RefSeq

Sequence: MDDSKVVGGKVKKPGKRGRKPAKIDLKAKLERSRQSARECRARKKLRYQYLEELVSSRERAICALREELEMYKQWCMAMDQGKIPSEIKALLTGEEQNKSQQNSSRHTKAGKTDANSNSW
Specifications

Specifications

cAMP responsive element binding protein-like 2
Unconjugated
No additive
NM_001310.2
MGC117311|MGC138362
Mouse
50 uL
Stem Cell Biology
Y
Polyclonal
Human
Western Blot
Mouse polyclonal antibody raised against a full-length human CREBL2 protein.
CREBL2
Serum
CREBL2
CREBL2 (NP_001301.1, 1 a.a. ~ 120 a.a) full-length human protein.
RUO
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Primary
1389
Documents
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