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CRH, Rabbit, Monoclonal Antibody, Abnova™

Catalog No. 89205490 Shop All Abnova Corporation Products
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1 mg x up to 3 Abs
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Catalog No. Quantity
89-205-490 1 mg x up to 3 Abs
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Catalog No. 89-205-490 Supplier Abnova Corporation Supplier No. H00001392K

Description

Includes

Up to three rabbit IgG clones of 1mg each will be delivered to customer.

Rabbit monoclonal antibody raised against a human CRH peptide using ARM Technology.

Corticotropin-releasing hormone (CRH) is a 41-amino acid peptide derived from a 191-amino acid preprohormone. CRH is secreted by the paraventricular nucleus (PVN) of the hypothalamus in response to stress. Marked reduction in CRH has been observed in association with Alzheimer disease and autosomal recessive hypothalamic corticotropin dificiency has multiple and potentially fatal metabolic consequences including hypoglycemia and hepatitis. In addition to production in the hypothalamus, CRH is also synthesized in peripheral tissues, such as T lymphocytes and is highly expressed in the placenta. In the placenta CRH is a marker that determines the length of gestation and the timing of parturition and delivery. A rapid increase in circulating levels of CRH occurs at the onset of parturition, suggesting that, in addition to its metabolic functions, CRH may act as a trigger for parturition. [provided by RefSeq

Library Construction: Nonfusion antibody library from rabbit spleen (ARM Technology)
Expression: Overexpression vector and transfection into 293H cell line

Order Info

  1. Customer may provide cell or tissue lysate for antibody screening.
  2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.

Specifications

Antigen CRH
Applications ELISA, Western Blot
Classification Monoclonal
Concentration 1mg
Conjugate Unconjugated
Description corticotropin releasing hormone
Formulation In 1X PBS, pH 7.4
Gene CRH
Gene Accession No. CRH
Gene Alias CRF
Gene Symbols CRH
Host Species Rabbit
Immunogen A synthetic peptide of human CRH
Quantity 1 mg x up to 3 Abs
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1392
Target Species Human
Content And Storage Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Form Liquid
Isotype IgG
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