anti-CRTH-2, Alexa Fluor 488, Clone: 301109, R&D Systems™

Chemoattractant Receptor-homologous Molecule Expressed on Th2 Cells

Supplier:  R&D Systems FAB33381G

Catalog No. FAB33381G

Description

CRTH-2 is a 7-transmembrane G-protein coupled receptor that is expressed by activated Th2 cells and eosinophils. CRTH-2 binds prostaglandin D2 and induces chemotaxis of Th2 cells and eosinophils in allergic and inflammatory immune responses. Human and mouse CRTH-2 share 78% amino acid sequence identity.

Host Species: Mouse
Clone: 301109
Isotype: IgG2A
Species Reactivity: Hu
Immunogen: NS0 mouse myeloma cell line transfected with human CRTH-2. Met1-Ser395; Accession Number Q9Y5Y4

Applications:

Flow Cytometry

Order Info

The product is shipped with polar packs.

Specifications

• Antigen: CRTH-2/GPR44
• Classification: Monoclonal
• Conjugate: Alexa Fluor 488
• Formulation: Supplied in a saline solution containing BSA and Sodium Azide. with Sodium Azide
• Gene Alias: CD294, CD294 antigen, Chemoattractant receptor-homologous molecule expressed on Th2 cells, CRTH2, CRTH2chemoattractant receptor homologous molecule expressed on T helper type 2 cells, DL1R, DP2, G protein-coupled receptor 44, GPR44, PGD2R, PTGDR2, putative G-protein coupled receptor 44
• Host Species: Mouse
• Purification Method: Protein A or G purified from hybridoma culture supernatant
• Regulatory Status: RUO
• Gene ID (Entrez): 11251
• Target Species: Human
• Form: Purified

• Applications: Flow Cytometry
• Clone: 301109
• Dilution: Flow Cytometry 5 uL/10^6 cells
• Gene Accession No.: Q9Y5Y4
• Gene Symbols: PTGDR2
• Immunogen: NS0 mouse myeloma cell line transfected with human CRTH-2, Met1-Ser395, Accession # Q9Y5Y4
• Quantity: 100 Tests
• Primary or Secondary: Primary
• Test Specificity: Detects human CRTH-2 in Cell-Based ELISA.
• Content And Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied.
• Isotype: IgG2a