Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
Our pricing system is unavailable. You are viewing list price.
Please call 1-800-766-7000 to place your order or try our site again later.

Csk Mouse, Unlabeled, Clone: 52, BD

Mouse Monoclonal Antibody

Specifications

Antigen Csk
Isotype IgG1
Immunogen Rat Csk aa. 1-156
Formulation Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Conjugate Unconjugated
View More Specs

Products 2
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
BDB610079
View Documents Promotion Details
BD Biosciences
610079
50μg
Each for $232.00
N/A
BDB610080
View Documents Promotion Details
BD Biosciences
610080
150μg This item has been discontinued and is no longer available. Please call customer service for assistance: 1-800-766-7000. N/A
Description

Description

The csk gene encodes a protein kinase that phosphorylates several Src family kinases including p60(c-src), p59(fyn), p53/56(lyn), p56(lck), and p62(yes). This phosphorylation occurs specifically at the carboxy-terminal tyrosine, Y527. Csk (c-src kinase) was identified based on its ability to phosphorylate exogenous Src in mammalian src-deficient cells. Establishment of a mouse csk- cell line revealed that phosphorylation of Y527 in Src was reduced 20-50%. This correlated with an increase of Src kinase activity, thus indicating Csk is a negative regulator of src. Csk-deficient cells also show an elevation in the kinase activity of p59(fyn) and p53/56(lyn). These data suggest that Csk may be a universal negative regulator of Src family kinases in vivo.

Host Species: Mouse
Clone: 52
Isotype: IgG1
Species Reactivity: Mouse
Immunogen: Rat Csk aa. 1-156
Formula Weight [Chemical]: 50kDa

Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blotting

Specifications

Specifications

Csk
Rat Csk aa. 1-156
Unconjugated
Cell Biology
Mouse
Affinity Purified
Monoclonal
Store undiluted at -20°C.
IgG1
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Primary
Western Blot
RUO
52
250μg/mL
SDS
Product Certifications

For Research Use Only.

Provide Content Correction

We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Cancel Submit