CST3, Mouse, Clone: 1H4, Abnova™

Catalog No.	Quantity
89-021-200	100 μg

Catalog No. 89-021-200 Supplier Abnova Corporation Supplier No. H00001471M04

Description

Mouse monoclonal antibody raised against a full-length native CST3.

The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions, where they appear to provide protective functions. The cystatin locus on chromosome 20 contains the majority of the type 2 cystatin genes and pseudogenes. This gene is located in the cystatin locus and encodes the most abundant extracellular inhibitor of cysteine proteases, which is found in high concentrations in biological fluids and is expressed in virtually all organs of the body. A mutation in this gene has been associated with amyloid angiopathy. Expression of this protein in vascular wall smooth muscle cells is severely reduced in both atherosclerotic and aneurysmal aortic lesions, establishing its role in vascular disease. [provided by RefSeq

Specifications

• Antigen: CST3
• Applications: ELISA, Western Blot
• Classification: Monoclonal
• Clone: 1H4
• Conjugate: Unconjugated
• Description: Mouse monoclonal antibody raised against a full length native CST3.
• Dilution: The optimal working dilution should be determined by the end user.
• Formulation: PBS with no preservative; pH 7.4
• Gene: CST3
• Gene Accession No.: P01034
• Gene Alias: ARMD11/MGC117328
• Gene Symbols: CST3
• Host Species: Mouse
• Immunogen: Native purified human CST3.
• Purification Method: Affinity chromatography
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 1471
• Target Species: Human
• Content And Storage: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG2a κ