CST3, Rabbit, Monoclonal Antibody, Abnova™

Catalog No.	Quantity
89-200-196	1 mg x up to 3 Abs

Catalog No. 89-200-196 Supplier Abnova Corporation Supplier No. H00001471K

Description

Includes

Up to three rabbit IgG clones of 1mg each will be delivered to customer.

Rabbit monoclonal antibody raised against a human CST3 peptide using ARM Technology.

The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions, where they appear to provide protective functions. The cystatin locus on chromosome 20 contains the majority of the type 2 cystatin genes and pseudogenes. This gene is located in the cystatin locus and encodes the most abundant extracellular inhibitor of cysteine proteases, which is found in high concentrations in biological fluids and is expressed in virtually all organs of the body. A mutation in this gene has been associated with amyloid angiopathy. Expression of this protein in vascular wall smooth muscle cells is severely reduced in both atherosclerotic and aneurysmal aortic lesions, establishing its role in vascular disease. [provided by RefSeq

Library Construction: Nonfusion antibody library from rabbit spleen (ARM Technology)
Expression: Overexpression vector and transfection into 293H cell line

Order Info

1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.

Specifications

• Antigen: CST3
• Applications: ELISA, Western Blot
• Classification: Monoclonal
• Concentration: 1mg
• Conjugate: Unconjugated
• Description: cystatin C
• Formulation: In 1X PBS, pH 7.4
• Gene: CST3
• Gene Accession No.: CST3
• Gene Alias: ARMD11, MGC117328
• Gene Symbols: CST3
• Host Species: Rabbit
• Immunogen: A synthetic peptide of human CST3
• Quantity: 1 mg x up to 3 Abs
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 1471
• Target Species: Human
• Content And Storage: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
• Form: Liquid
• Isotype: IgG