MilliporeSigma™ anti-CTCF, Polyclonal

Supplier:  MilliporeSigma™ 07729/DEL

Catalog No. 50-172-614

Description

CTCF is a ubiquitous 11 zinc finger (ZF) protein with highly versatile functions. A transcriptional repressor, CTCF, binds to promoters of vertebrate c-myc gene. It also binds to the PLK and PIM1 promoters. CTCF may prevent the access of transcriptional activators to enhancers. CTCF also acts as a transcriptional activator of APP. It is involved in different aspects of gene regulation including promoter activation or repression, hormone-responsive gene silencing, methylation-dependent chromatin insulation, and genomic imprinting. CTCF may also act as tumor suppressor. CTCF organizes epigenetically controlled chromatin insulators that regulate imprinted genes in soma. GenBank Number: AAB07788. MW: 120kDa.

Chromatin Immunoprecipitation, Western Blotting

Specifications

• Antigen: CTCF
• Conjugate: Unconjugated
• Immunogen: KLH-conjugated, synthetic peptide corresponding to amino acids 659-675 (C-TNQPKQNQPTAIIQVED) of human CCCTC-binding factor (CTCF) with a N-terminal cysteine added for conjugation purposes
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Form: Serum

• Classification: Polyclonal
• Host Species: Rabbit
• Quantity: 200 μg
• Research Discipline: Epigenetics
• Target Species: Canine, Human, Mouse, Rat