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MilliporeSigma™ anti-CTCF, Polyclonal
Supplier: MilliporeSigma™ 07729/DEL

Description
CTCF is a ubiquitous 11 zinc finger (ZF) protein with highly versatile functions. A transcriptional repressor, CTCF, binds to promoters of vertebrate c-myc gene. It also binds to the PLK and PIM1 promoters. CTCF may prevent the access of transcriptional activators to enhancers. CTCF also acts as a transcriptional activator of APP. It is involved in different aspects of gene regulation including promoter activation or repression, hormone-responsive gene silencing, methylation-dependent chromatin insulation, and genomic imprinting. CTCF may also act as tumor suppressor. CTCF organizes epigenetically controlled chromatin insulators that regulate imprinted genes in soma. GenBank Number: AAB07788. MW: 120kDa.
Chromatin Immunoprecipitation, Western Blotting

Specifications
CTCF | |
Unconjugated | |
KLH-conjugated, synthetic peptide corresponding to amino acids 659-675 (C-TNQPKQNQPTAIIQVED) of human CCCTC-binding factor (CTCF) with a N-terminal cysteine added for conjugation purposes | |
RUO | |
Primary | |
Serum |
Polyclonal | |
Rabbit | |
200 μg | |
Epigenetics | |
Canine, Human, Mouse, Rat |
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