CXCR7 Rabbit anti-Human, Mouse, Rat, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA3069

Catalog No. PIPA3069

Description

PA3-069 detects CXC Chemokine Receptor Type 7 from human and mouse samples. PA3-069 has been successfully used in Western blot and immunocytochemistry procedures. By Western blot, this antibody detects a 42 kDa protein corresponding to mouse CXC Chemokine Receptor Type 7. The PA3-069 antigen is the COOH-terminal amino acids of mouse CXCR7 (347–362) SRVSETEYSALEQNTK coupled to KLH.

C-X-C chemokine receptor type 7 (CXCR-7) is a protein member of the G-protein coupled receptor family. Although this protein was earlier thought to be a receptor for vasoactive intestinal peptide (VIP), it was considered to be an orphan receptor, because its endogenous ligand has not been identified. It is now classified as a chemokine receptor able to bind the chemokines CXCL12/SDF-1 and CXCL11. The protein is also a coreceptor for human immunodeficiency viruses (HIV). Translocations involving this gene and HMGA2 on chromosome 12 have been observed in lipomas.

Specifications

• Antigen: CXCR7
• Classification: Polyclonal
• Formulation: whole serum with 0.02% sodium azide
• Gene Accession No.: P25106, P56485, O89039
• Gene Alias: C-X-C chemokine receptor type 7, CXC-R7, CXCR-7, G-protein coupled receptor RDC1 homolog, RDC-1, chemokine
• Host Species: Rabbit
• Isotype: IgG
• Regulatory Status: RUO
• Type: Antibody
• Monoclonal or Polyclonal: Polyclonal
• Target Species: Human, Mouse, Rat

• Applications: Immunocytochemistry, Immunofluorescence, Western Blot
• Conjugate: Unconjugated
• Gene: ACKR3
• Format: Liquid
• Gene Symbols: ACKR3
• Immunogen: COOH-terminal amino acids of mouse CXCR7 (347–362) SRVSETEYSALEQNTK coupled to KLH.
• Quantity: 100 μL
• Storage Requirements: -20° C, Avoid Freeze/Thaw Cycles
• Primary or Secondary: Primary
• Gene ID (Entrez): 12778, 57007, 84348