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CXCR7 Rabbit anti-Human, Mouse, Rat, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA3069

Catalog No. PIPA3069


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Description

Description

PA3-069 detects CXC Chemokine Receptor Type 7 from human and mouse samples. PA3-069 has been successfully used in Western blot and immunocytochemistry procedures. By Western blot, this antibody detects a 42 kDa protein corresponding to mouse CXC Chemokine Receptor Type 7. The PA3-069 antigen is the COOH-terminal amino acids of mouse CXCR7 (347–362) SRVSETEYSALEQNTK coupled to KLH.

C-X-C chemokine receptor type 7 (CXCR-7) is a protein member of the G-protein coupled receptor family. Although this protein was earlier thought to be a receptor for vasoactive intestinal peptide (VIP), it was considered to be an orphan receptor, because its endogenous ligand has not been identified. It is now classified as a chemokine receptor able to bind the chemokines CXCL12/SDF-1 and CXCL11. The protein is also a coreceptor for human immunodeficiency viruses (HIV). Translocations involving this gene and HMGA2 on chromosome 12 have been observed in lipomas.
Specifications

Specifications

CXCR7
Polyclonal
whole serum with 0.02% sodium azide
P25106, P56485, O89039
C-X-C chemokine receptor type 7, CXC-R7, CXCR-7, G-protein coupled receptor RDC1 homolog, RDC-1, chemokine
Rabbit
IgG
RUO
Antibody
Polyclonal
Human, Mouse, Rat
Immunocytochemistry, Immunofluorescence, Western Blot
Unconjugated
ACKR3
Liquid
ACKR3
COOH-terminal amino acids of mouse CXCR7 (347–362) SRVSETEYSALEQNTK coupled to KLH.
100 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
12778, 57007, 84348
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