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CXCR5 Rat anti-Human, Alexa Fluor 647, Clone: RF8B2, BD

Catalog No. BDB558113 Shop All BD Biosciences Products
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Catalog No. BDB558113 Supplier BD Biosciences Supplier No. 558113
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Rat Monoclonal Antibody

The monoclonal antibody RF8B2 reacts with the human CXC chemokine receptor, CXCR5. CXCR5 (aka BLR-1 NLR and MDR15), a seven transmembrane, G-protein-coupled receptor, is the specific receptor for CXC chemokine, CXCL13/BLC/BCA-1. In peripheral blood, CXCR5 expression is restricted to B lymphocytes and a small subset of CD4+ and CD8+ lymphocytes. The restricted expression pattern of CXCR5 on B cells suggested that this receptor might function as a regulator of B cell migration. Stimulation of T cells with anti-CD3 monoclonal antibody leads to the down-regulation of CXCR5.

TRUSTED_SUSTAINABILITY

Specifications

Antigen CXCR5
Applications Flow Cytometry
Classification Monoclonal
Clone RF8B2
Concentration 0.2mg/mL
Conjugate Alexa Fluor 647
Formulation Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species Rat
Immunogen Human CXCR5
Purification Method Affinity Purified
Quantity 0.1 mg
Regulatory Status RUO
Research Discipline Immunology
Primary or Secondary Primary
Target Species Human
Content And Storage Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Isotype IgG2b κ
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WARNING: Reproductive Harm - www.P65Warnings.ca.gov

For Research Use Only.

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