CXCR5 Rat anti-Human, Alexa Fluor 647, Clone: RF8B2, BD

Rat Monoclonal Antibody

Supplier:  BD Biosciences 558113

Catalog No. BDB558113

Description

The monoclonal antibody RF8B2 reacts with the human CXC chemokine receptor, CXCR5. CXCR5 (aka BLR-1 NLR and MDR15), a seven transmembrane, G-protein-coupled receptor, is the specific receptor for CXC chemokine, CXCL13/BLC/BCA-1. In peripheral blood, CXCR5 expression is restricted to B lymphocytes and a small subset of CD4+ and CD8+ lymphocytes. The restricted expression pattern of CXCR5 on B cells suggested that this receptor might function as a regulator of B cell migration. Stimulation of T cells with anti-CD3 monoclonal antibody leads to the down-regulation of CXCR5.

Specifications

• Antigen: CXCR5
• Classification: Monoclonal
• Concentration: 0.2mg/mL
• Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
• Immunogen: Human CXCR5
• Quantity: 0.1 mg
• Research Discipline: Immunology
• Target Species: Human
• Isotype: IgG2b κ

• Applications: Flow Cytometry
• Clone: RF8B2
• Conjugate: Alexa Fluor 647
• Host Species: Rat
• Purification Method: Affinity Purified
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Safety and Handling

WARNING: Reproductive Harm - www.P65Warnings.ca.gov

For Research Use Only.