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Description
The monoclonal antibody RF8B2 reacts with the human CXC chemokine receptor, CXCR5. CXCR5 (aka BLR-1 NLR and MDR15), a seven transmembrane, G-protein-coupled receptor, is the specific receptor for CXC chemokine, CXCL13/BLC/BCA-1. In peripheral blood, CXCR5 expression is restricted to B lymphocytes and a small subset of CD4+ and CD8+ lymphocytes. The restricted expression pattern of CXCR5 on B cells suggested that this receptor might function as a regulator of B cell migration. Stimulation of T cells with anti-CD3 monoclonal antibody leads to the down-regulation of CXCR5.
Specifications
Specifications
| Antigen | CXCR5 |
| Applications | Flow Cytometry |
| Classification | Monoclonal |
| Clone | RF8B2 |
| Concentration | 0.2mg/mL |
| Conjugate | Alexa Fluor 647 |
| Formulation | Aqueous buffered solution containing ≤0.09% sodium azide. |
| Host Species | Rat |
| Immunogen | Human CXCR5 |
| Purification Method | Affinity Purified |
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Safety and Handling
For Research Use Only.
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