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CXCR5 Rat anti-Mouse, Brilliant Violet 421, Clone: 2G8, BD

Catalog No. BDB562889 Shop All BD Biosciences Products
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BDB562889 50 μg
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Catalog No. BDB562889 Supplier BD Biosciences Supplier No. 562889
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Description

Rat Monoclonal Antibody

The 2G8 monoclonal antibody specifically binds to the mouse CXC chemokine receptor, CXCR5. CXCR5 is also known as CD185, BLR1, NLR and MDR15. CXCR5 is a seven-transmembrane, G-protein-coupled receptor that is specific for the CXC chemokine, CXCL13/BLC/BCA-1. The expression of CXCR5 has been detected in spleen, lymph nodes, tonsils, brain, bone marrow, T cells, B cells, cerebrum, cerebellum, hippcampus and pituitary. In mouse spleen, CXCR5 was strictly expressed by mature B cells and a small subset of T lymphocytes. CXCR5 plays a role in directing the migration of B and T cells to B cell follicles with the spleen and certain other lymphoid tissues. The immunogen used to generate 2G8 hybridoma was a recombinant protein containing N-terminal amino acids of mouse CXCR5 (GST-NmBLR1).

The antibody was conjugated to BD Horizon™ BV421 which is part of the BD Horizon™ Brilliant Violet™ family of dyes. With an Ex Max of 407-nm and Em Max at 421-nm, BD Horizon™ BV421 can be excited by the violet laser and detected in the standard Pacific Blue™ filter set (eg, 450/50-nm filter). BD Horizon™ BV421 conjugates are very bright, often exhibiting a 10 fold improvement in brightness compared to Pacific Blue™ conjugates.

TRUSTED_SUSTAINABILITY

Specifications

Antigen CXCR5
Applications Flow Cytometry
Classification Monoclonal
Clone 2G8
Concentration 0.2mg/mL
Conjugate Brilliant Violet 421
Description CD185; CXC-R5; CXCR-5; C-X-C chemokine receptor type 5; Blr1; MDR15; Gpcr6
Formulation Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Host Species Rat
Immunogen Mouse CXCR5
Purification Method Affinity Purified
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Target Species Mouse
Content And Storage Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Isotype IgG2a κ
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