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CXCR5 Rat anti-Mouse, BUV395, Clone: 2G8, BD

Catalog No. BDB563980 Shop All BD Biosciences Products
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BDB563980 50 μg
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Catalog No. BDB563980 Supplier BD Biosciences Supplier No. 563980
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Description

Rat Monoclonal Antibody

The 2G8 monoclonal antibody specifically binds to the mouse CXC chemokine receptor, CXCR5. CXCR5 is also known as CD185, BLR1, NLR and MDR15. CXCR5 is a seven-transmembrane, G-protein-coupled receptor that is specific for the CXC chemokine, CXCL13/BLC/BCA-1. The expression of CXCR5 has been detected in spleen, lymph nodes, tonsils, brain, bone marrow, T cells, B cells, cerebrum, cerebellum, hippcampus and pituitary. In mouse spleen, CXCR5 was strictly expressed by mature B cells and a small subset of T lymphocytes. CXCR5 plays a role in directing the migration of B and T cells to B cell follicles with the spleen and certain other lymphoid tissues. The immunogen used to generate 2G8 hybridoma was a recombinant protein containing N-terminal amino acids of mouse CXCR5 (GST-NmBLR1).

The antibody was conjugated to BD Horizon™ BUV395 which has been exclusively developed by BD Biosciences as an optimal dye for use on a 355nm laser equipped instrument. With an Ex Max at 348 nmand an Em Max at 395nm, this dye has virtually no spillover into any other detector. BD Horizon BUV395 can be excited with a 355nm laser and detected with a 379/28 filter.

TRUSTED_SUSTAINABILITY

Specifications

Antigen CXCR5
Applications Flow Cytometry
Classification Monoclonal
Clone 2G8
Concentration 0.2mg/mL
Conjugate Brilliant Ultraviolet 395
Description CD185; CXC-R5; CXCR-5; C-X-C chemokine receptor type 5; Blr1; MDR15; Gpcr6
Formulation Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Host Species Rat
Immunogen Mouse CXCR5
Purification Method Affinity Purified
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Target Species Mouse
Content And Storage Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Isotype IgG2a κ
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