anti-Cyclin D1/Bcl-1, Clone: SP4, Epredia™ LabVision

The Epredia™ Cyclin D1/Bcl-1, Rabbit Monoclonal Antibody is part of a comprehensive antibody portfolio. Studies show rabbit monoclonal antibodies are more sensitive and specific than other available markers.

Supplier:  Epredia RM9104R7

Catalog No. RM9104R7

Description

Cyclin D1 or PRAD-1 or bcl-1 is one of the key cell cycle regulators, and functions in association with cdk4 and/or cdk6 by phosphorylating the Rb protein. It is a putative proto-oncogene overexpressed in a wide variety of human neoplasms including mantle cell lymphomas (MCL).

Host Species: Rabbit
Clone: SP4
Isotype: IgG
Species Reactivity: Human, Mouse, Rat. Others not tested.
Epitope: C-terminus
Immunogen: A synthetic peptide from C-terminus of human cyclin D1
Molecular Weight: 36kDa
Positive Control: MAD109 cells, breast CA or mantle cell lymphoma
Cellular Localization: Nuclear

Clone SP4 is excellent for staining of formal/paraffin tissue.

†USA: IVD; Int'l: IVD

Immunohistochemistry (Paraffin), Western Blotting

Specifications

• Antigen: Cyclin D1/Bcl-1
• Clone: SP4
• Conjugate: Unconjugated
• Immunogen: A synthetic peptide from C-terminus of human cyclin D1
• Regulatory Status: IVD
• Primary or Secondary: Primary
• Form: Prediluted

• Classification: Monoclonal
• Concentration: n/a
• Host Species: Rabbit
• Quantity: 7 mL
• Research Discipline: Cell Cycle
• Target Species: Human, Mouse, Rat
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov