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Cyclin F Rabbit anti-Human, Polyclonal, Invitrogen™
Rabbit Polyclonal Antibody
Supplier: Thermo Scientific PA527836
Description
PA5-27836 targets Cyclin F in WB applications and shows reactivity with Human samples. The PA5-27836 immunogen is recombit fragment corresponding to a region within amino acids 444 and 786 of Human Cyclin F. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.
This gene encodes a member of the cyclin family. Cyclins are important regulators of cell cycle transitions through their ability to bind and activate cyclin-dependent protein kinases. This member also belongs to the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and it was one of the first proteins in which the F-box motif was identified.
Specifications
Cyclin F | |
Polyclonal | |
Unconjugated | |
P41002 | |
CCNF | |
Recombit fragment corresponding to a region within amino acids 444 and 786 of Human Cyclin F | |
100 μL | |
Primary | |
Human | |
Antibody | |
IgG |
Western Blot | |
1 mg/mL | |
CCNF | |
FBX1, FBXO1, F-box only protein 1, G2/mitotic-specific cyclin-F, cyclin-F | |
Rabbit | |
Antigen affinity chromatography | |
RUO | |
899 | |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
Liquid |
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