CYP3A7, Rabbit, Monoclonal Antibody, Abnova™

Rabbit monoclonal antibody raised against a human CYP3A7 peptide using ARM Technology.

Supplier:  Abnova Corporation H00001551K

Catalog No. 89-205-060

Includes: Up to three rabbit IgG clones of 1mg each will be delivered to customer.

Description

This gene, CYP3A7, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This enzyme hydroxylates testosterone and dehydroepiandrosterone 3-sulphate, which is involved in the formation of estriol during pregnancy. The enzyme also metabolizes some drugs such as aflatoxin B1. This gene is part of a cluster of cytochrome P450 genes on chromosome 7q21.1. Transcript variants have been described, but it is not known whether these transcripts are normally produced. [provided by RefSeq

Library Construction: Nonfusion antibody library from rabbit spleen (ARM Technology)
Expression: Overexpression vector and transfection into 293H cell line

Order Info

1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.

Specifications

• Antigen: CYP3A7
• Classification: Monoclonal
• Conjugate: Unconjugated
• Formulation: In 1X PBS, pH 7.4
• Gene Accession No.: CYP3A7
• Gene Symbols: CYP3A7
• Immunogen: A synthetic peptide of human CYP3A7
• Regulatory Status: RUO
• Gene ID (Entrez): 1551
• Content And Storage: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
• Isotype: IgG

• Applications: ELISA, Western Blot
• Concentration: 1mg
• Description: cytochrome P450, family 3, subfamily A, polypeptide 7
• Gene: CYP3A7
• Gene Alias: CP37, P450-HFLA
• Host Species: Rabbit
• Quantity: 1 mg x up to 3 Abs
• Primary or Secondary: Primary
• Target Species: Human
• Form: Liquid