MilliporeSigma™ anti-Cytokeratin 5, 6, Clone: D5/16B4, ™ (Chemicon™)

Supplier:  MilliporeSigma™ MAB1620/DEL

Catalog No. 50-174-893

Description

The cytokeratins are a family of intermediate filaments fond in almost all epithelial cells. They are divided into four subclasses depending on their patterns of reactivity and electrophoretic characteristics and are also arranged I a numbered series of 20 or more acoring to molecular weight and isoelectric point (Quinlan et al. 1985). Types 5 and 6 of cytokeratin (CK5/6) are in high frequency in mesothelial cells, as opposed to cells of adenocarcinoma. CK5/6 has been shown to be a reliable marker for mesothelioma and squamous cell carcinoma of the lung and Bowen's disease. It does not react with pulmonary adenocarcinoma.

Wild & Mischke, 1986; Mischke & Wild, 1987

Immunofluorescence, Immunohistochemistry (Paraffin), Western Blotting

Specifications

• Antigen: Cytokeratin 5, 6
• Conjugate: Unconjugated
• Immunogen: Purified cytokeratin 5
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Form: Semi-purified

• Classification: Monoclonal
• Host Species: Mouse
• Quantity: 50 μg
• Research Discipline: Cell Structure
• Target Species: Human, Mouse, Rat
• Isotype: IgG1