Cytokeratin 6A Monoclonal Antibody (LHK6B), Invitrogen™

Mouse Monoclonal Antibody

Supplier:  Thermo Scientific MA514127

Catalog No. PIMA514127

Description

MA5-14127 targets Cytokeratin 6 in FN applications and shows reactivity with Human and mouse samples. The MA5-14127 immunogen is a synthetic peptide (GSSTIKYTTTS) from the C-terminus of human keratin 6.

Keratins 6 and 16 are expressed in keratinocytes, which are undergoing rapid turnover in the suprabasal region (also known as hyperproliferation-related keratins). Keratin 6 is found in hair follicles, suprabasal cells of a variety of internal stratified epithelia, in epidermis, in both normal and hyperproliferative situations. Epidermal injury results in activation of keratinocytes which express CK6 and CK16. CK6 is strongly expressed in about 75% of head and neck squamous cell carcinomas. Expression of CK6 is particularly associated with differentiation.

Specifications

• Antigen: Cytokeratin 6A
• Classification: Monoclonal
• Concentration: 0.2 mg/mL
• Formulation: PBS with 0.2% BSA and 0.09% sodium azide; pH 7.4
• Gene Accession No.: P02538, P50446
• Gene Symbols: KRT6A
• Immunogen: A synthetic peptide (GSSTIKYTTTS) from the C-terminus of human keratin 6
• Quantity: 500 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG2a

• Applications: Immunohistochemistry
• Clone: LHK6B
• Conjugate: Unconjugated
• Gene: KRT6A
• Gene Alias: 2310016L08Rik; 60-kDa keratin; CK6A; CK-6A; CK6C; CK-6C; CK6D; CK-6D; CK-6E; cytokeratin 6A; cytokeratin 6C; cytokeratin 6D; cytokeratin-6A; cytokeratin-6C; Cytokeratin-6D; cytokeratin-6E; Hom s 5; K6A; K6a keratin; K6C; K6D; kamp-keratin derived antimicrobial peptide; KDAMP; Ker2; keratin 6A; keratin 6A, , type II; keratin 6A, type II; keratin complex 2, basic, gene 6a; keratin complex 2, basic, gene 6c; keratin complex 2, gene 6a; keratin K6; keratin K6h; keratin, epidermal type II, K6A; keratin, type II cytoskeletal 6A; keratin, type II cytoskeletal 6C; Keratin-6A; keratin-6-alpha; keratin-6C; Krt2-6; Krt2-6a; Krt2-6c; Krt6; KRT6A; KRT6C; KRT6D; LOC683313; mK6[a]; MK6a; mK6-alpha; PC3; similar to keratin complex 2, basic, gene 6a; type-II keratin Kb12; type-II keratin Kb6
• Host Species: Mouse
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 16687, 3853
• Content And Storage: 4° C
• Form: Liquid

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov