D107a Mouse anti-Human, Brilliant Violet 786, Clone: H4A3, BD

Catalog No.	Quantity
BDB563869	50 Tests

Catalog No. BDB563869 Supplier BD Biosciences Supplier No. 563869

Description

Mouse Monoclonal Antibody

The H4A3 monoclonal antibody specifically binds to the heavily glycosylated 110 kDa Lysosomal-associated membrane protein 1, LAMP-1. LAMP-1 is a widely expressed intracellular antigen. It is also expressed on the surface of activated platelets, PHA-activated lymphocytes, cytotoxic T cells and NK cells, and some tumor cell lines, including U937 and KG1a. LAMP-1 has been shown to be a ligand for E-selectin-mediated cell adhesion. LAMP-1 and LAMP-2 (CD107b) are carriers for poly-N-acetyllactosamines and are able to display sialyl Le[x] termini.

The antibody was conjugated to BD Horizon™ BV786 which is part of the BD Horizon™ Brilliant Violet™ family of dyes. This dye is a tandem fluorochrome of BD Horizon™ BV421 with an Ex Max of 405-nm and an acceptor dye with an Em Max at 786-nm. BD Horizon™ BV786 can be excited by the violet laser and detected in a filter used to detect Cy™7-like dyes (eg, 780/60-nm filter).

Specifications

• Antigen: D107a
• Applications: Flow Cytometry
• Classification: Monoclonal
• Clone: H4A3
• Conjugate: Brilliant Violet 786
• Description: LAMP1; LAMP-1; LAMPA; LGP120
• Formulation: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
• Host Species: Mouse
• Immunogen: Human Adult Adherent Peripheral Blood Cells
• Purification Method: Affinity Purified
• Quantity: 50 Tests
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Target Species: Human
• Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
• Isotype: IgG1 κ