DCLK1 Rabbit anti-Human, Mouse, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Supplier:  Thermo Scientific PA514046

Catalog No. PIPA514046

Description

Doublecortin-like kinase (DCAMKL1)(Ser/Thr protein kinase family) is essential for proper neurogenesis, neuronal migration, and axonal wiring. DCAMKL1 is involved in a calcium-signaling pathway controling neuronal migration in the developing brain, and participates in functions of the mature nervous system. DCAMKL1 protein shares high homology with doublecortin (DCX). DCLK, but not DCX, is highly expressed in regions of active neurogenesis in the neocortex and cerebellum. DCAMKL1 controls mitotic division by regulating spindle formation and also determines the fate of neural progenitors during cortical neurogenesis.

Specifications

• Antigen: DCLK1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene Accession No.: O15075, Q9JLM8
• Gene Symbols: DCLK1
• Immunogen: KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human DCAMKL1
• Quantity: 400 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG

• Applications: Western Blot
• Concentration: 0.5 mg/mL
• Gene: DCLK1
• Gene Alias: Serine/threonine-protein kinase DCAMKL1, Doublecortin-like and CAM kinase-like 1
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 13175, 9201
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid