damage-specific DNA binding protein 1, 127kDa, Mouse, Polyclonal Antibody, Abnova
Mouse polyclonal antibody raised against a partial recombinant DDB1.
Manufacturer: Abnova Corporation H00001642A01
This gene encodes the large subunit of DNA damage-binding protein which is a heterodimer composed of a large and a small subunit. This protein functions in nucleotide-excision repair. Its defective activity causes the repair defect in the patients with xeroderma pigmentosum complementation group E (XPE). However, it remains for mutation analysis to demonstrate whether the defect in XPE patients is in this gene or the gene encoding the small subunit. In addition, Best vitelliform mascular dystrophy is mapped to the same region as this gene on 11q, but no sequence alternations of this gene are demonstrated in Best disease patients. [provided by RefSeqSequence: SESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH
|damage-specific DNA binding protein 1, 127kDa|
|Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.|
|ELISA, Western Blot|
|Mouse polyclonal antibody raised against a partial recombinant DDB1.|
|DDB1 (NP_001914, 1044 a.a. ~ 1140 a.a) partial recombinant protein with GST tag.|
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