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damage-specific DNA binding protein 1, 127kDa, Mouse, Polyclonal Antibody, Abnova™

Catalog No. 89004092 Shop All Abnova Corporation Products
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89-004-092 50 μL
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Catalog No. 89-004-092 Supplier Abnova Corporation Supplier No. H00001642A01
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Mouse polyclonal antibody raised against a partial recombinant DDB1.

This gene encodes the large subunit of DNA damage-binding protein which is a heterodimer composed of a large and a small subunit. This protein functions in nucleotide-excision repair. Its defective activity causes the repair defect in the patients with xeroderma pigmentosum complementation group E (XPE). However, it remains for mutation analysis to demonstrate whether the defect in XPE patients is in this gene or the gene encoding the small subunit. In addition, Best vitelliform mascular dystrophy is mapped to the same region as this gene on 11q, but no sequence alternations of this gene are demonstrated in Best disease patients. [provided by RefSeq

Sequence: SESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH

Specifications

Antigen damage-specific DNA binding protein 1, 127kDa
Applications ELISA, Western Blot
Classification Polyclonal
Conjugate Unconjugated
Description Mouse polyclonal antibody raised against a partial recombinant DDB1.
Formulation 50% glycerol
Gene DDB1
Gene Accession No. NM_001923
Gene Alias DDBA/UV-DDB1/XAP1/XPCE/XPE/XPE-BF
Gene Symbols DDB1
Host Species Mouse
Immunogen DDB1 (NP_001914, 1044 a.a. ∼ 1140 a.a) partial recombinant protein with GST tag.
Quantity 50 μL
Regulatory Status RUO
Whole Molecule Yes
Primary or Secondary Primary
Gene ID (Entrez) 1642
Target Species Human
Content And Storage Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Form Serum
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