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DcTRAILR1 Rabbit anti-Mouse, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA141657

Catalog No. 01-675-268


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Description

Description

Mouse DcTRAILR1 and DcTRAILR2 (decoy TRAIL receptors 1 and 2) proteins are receptors for TRAIL according to ligand-receptor binding assays (Schneider et al. 2001).  However, overexpression does not cause NF-kB activation or apoptosis, as would be expected of a TRAIL receptor. These observations led researchers to refer to these receptors as decoys.  It is thought that cells that express decoy TRAIL receptor decoys at high levels relative to actual TRAIL receptors may use decoys as protection against the cytotoxic action of TRAIL (reviewed in Bouralexis et al. 2005). Additional analysis of these two murine TRAIL decoy receptors should help faciliate the understanding of the complex biology underlying TRAIL ligand/receptor interactions. DcTRAILR1 is an amino acid protein of 176 amino acids (GenBank no: NP-077252.2). DcTRAILR2 is an amino acid protein of 198 amino acids (GenBank no: AAN87807.1).

Suggested positive control: mouse spleen lysate or protein.
Specifications

Specifications

DcTRAILR1
Polyclonal
Unconjugated
PBS with 0.2% gelatin and 0.05% sodium azide
Q9ER63
Dctrailr1, MGC123882, MGC123883, Tnfrh1, Tnfrsf1al1, mDcTrailr1, mSOB
Rabbit
IgG
100 μg
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
79201
Western Blot
0.5 mg/mL
1-3ug/mL
Tnfrsf23
Liquid
TNFRSF23
Synthetic peptide corresponding to residues C(155) S S S V S N P R N W L F L(168) of mouse DcTrailR1.
Protein G
RUO
Antibody
Polyclonal
Mouse
Documents
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