Delta-Like Protein 1 Mouse anti-Human, PE, Clone: MHD1-314, BD

Mouse Monoclonal Antibody

Supplier:  BD Biosciences 564414

Catalog No. BDB564414

Description

The MHD1-314 monoclonal antibody specifically binds to Delta-Like Protein 1 which is also known as Delta1, DLL1, and DL1. Delta-Like Protein 1 is a type 1 transmembrane glycoprotein which belongs to the Delta/Serrate/Jagged Family of Notch receptor ligands. The Notch family of transmembrane receptors and their ligands play key roles in various developmental and postnatal processes by controlling cell-fate decisions. Delta-Like Protein 1 is expressed by cells within heart, pancreas, brain, muscle and hematopoietic/lymphoid tissues. This Notch ligand functions in the development and postnatal activities of the nervous and skeletal systems. It also functions in the hematopoietic and immune systems, for example, by promoting the differentiation of hematopoietic progenitors into T cell and NK cell precursors. The MHD1-314 antibody reportedly inhibits the development of osteoclasts from cultured peripheral blood monocytes suggesting that Delta-Like Protein 1 positively regulates osteoclastogenesis.

Specifications

• Antigen: Delta-Like Protein 1
• Classification: Monoclonal
• Concentration: 0.2mg/mL
• Description: DLL1; DL1; Delta1; H-Delta-1; Delta-like 1; Delta
• Host Species: Mouse
• Purification Method: Affinity Purified
• Regulatory Status: RUO
• Target Species: Human
• Isotype: IgG1 κ

• Applications: Flow Cytometry
• Clone: MHD1-314
• Conjugate: PE
• Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
• Immunogen: Human DLL1 Recombinant Protein
• Quantity: 50 μg
• Primary or Secondary: Primary
• Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.