Learn More
Description
This gene encodes a flavin adenine dinucleotide (FAD)-dependent oxidoreductase which catalyzes the reduction of the delta-24 double bond of sterol intermediates during cholesterol biosynthesis. The protein contains a leader sequence that directs it to the endoplasmic reticulum membrane. Missense mutations in this gene have been associated with desmosterolosis. Also, reduced expression of the gene occurs in the temporal cortex of Alzheimer disease patients and overexpression has been observed in adrenal gland cancer cells. [provided by RefSeq
Specifications
Specifications
| Antigen | DHCR24 |
| Applications | Western Blot |
| Classification | Polyclonal |
| Conjugate | Unconjugated |
| Description | Rabbit polyclonal antibody raised against a full-length human DHCR24 protein. |
| Formulation | PBS with no preservative; pH 7.4 |
| Gene | DHCR24 |
| Gene Accession No. | NM_014762.2 |
| Gene Alias | KIAA0018/Nbla03646/SELADIN1/seladin-1 |
| Gene Symbols | DHCR24 |
| Show More |
By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.