DHCR24 Rabbit anti-Human, Mouse, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Supplier:  Thermo Scientific PA512456

Catalog No. PIPA512456

Description

This antibody is predicted to react with non-human primate based on sequence homology.

DHCR24 is a flavin adenine dinucleotide (FAD)-dependent oxidoreductase which catalyzes the reduction of the delta-24 double bond of sterol intermediates during cholesterol biosynthesis. This protein contains a leader sequence that directs it to the endoplasmic reticulum membrane. Missense mutations in this gene have been associated with desmosterolosis. Also, reduced expression of its gene occurs in the temporal cortex of Alzheimer disease patients and overexpression has been observed in adrenal gland cancer cells.

Specifications

• Antigen: DHCR24
• Classification: Polyclonal
• Gene: DHCR24
• Gene Alias: 24-dehydrocholesterol reductase; 3-beta-hydroxysterol delta-24-reductase; Seladin-1; Diminuto/dwarf1 homolog; DHCR24
• Host Species: Rabbit
• Purification Method: Ammonium sulfate precipitation, Size-exclusion - Dialysis
• Regulatory Status: RUO
• Gene ID (Entrez): 1718, 74754
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot
• Conjugate: Unconjugated
• Gene Accession No.: Q15392, Q8VCH6
• Gene Symbols: DHCR24
• Immunogen: KLH conjugated synthetic peptide between 57-87 amino acids from the N-terminal region of human DHCR24
• Quantity: 400 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG