DHCR24 Rabbit anti-Human, Mouse, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA512456
This antibody is predicted to react with non-human primate based on sequence homology.DHCR24 is a flavin adenine dinucleotide (FAD)-dependent oxidoreductase which catalyzes the reduction of the delta-24 double bond of sterol intermediates during cholesterol biosynthesis. This protein contains a leader sequence that directs it to the endoplasmic reticulum membrane. Missense mutations in this gene have been associated with desmosterolosis. Also, reduced expression of its gene occurs in the temporal cortex of Alzheimer disease patients and overexpression has been observed in adrenal gland cancer cells.
|PBS with 0.09% sodium azide|
|24-dehydrocholesterol reductase; 3-beta-hydroxysterol delta-24-reductase; Seladin-1; Diminuto/dwarf1 homolog; DHCR24|
|-20° C, Avoid Freeze/Thaw Cycles|
|KLH conjugated synthetic peptide between 57-87 amino acids from the N-terminal region of human DHCR24|
|Ammonium sulfate precipitation, Size-exclusion - Dialysis|
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