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DHCR24 Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA512457

Catalog No. PIPA512457

This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.


Description

Description

This antibody is predicted to react with bovine, chicken, mouse and rat based on sequence homology.

DHCR24 is a flavin adenine dinucleotide (FAD)-dependent oxidoreductase which catalyzes the reduction of the delta-24 double bond of sterol intermediates during cholesterol biosynthesis. This protein contains a leader sequence that directs it to the endoplasmic reticulum membrane. Missense mutations in DHCR24 gene have been associated with desmosterolosis. Also, reduced expression of DHCR24 gene occurs in the temporal cortex of Alzheimer disease patients and overexpression has been observed in adrenal gland cancer cells.
Specifications

Specifications

DHCR24
Polyclonal
PBS with 0.09% sodium azide
Q15392
Diminuto/dwarf1 homolog; Seladin-1; 3-beta-hydroxysterol delta-24-reductase; 24-dehydrocholesterol reductase; DHCR24; KIAA0018
Rabbit
IgG
400 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
1718
Western Blot
Unconjugated
DHCR24
Liquid
DHCR24
KLH conjugated synthetic peptide between 218-246 amino acids from the central region of human DHCR24
Ammonium sulfate precipitation, Size-exclusion - Dialysis
RUO
Antibody
Polyclonal
Human
Documents
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