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Description
Diphthamide is a unique posttranslationally modified histidine found only in translation elongation factor-2 (EEF2; MIM 130610). This modification is conserved from archaebacteria to humans and serves as the target for ADP-ribosylation and inactivation of EEF2 by diphtheria toxin (DT) and Pseudomonas exotoxin A. DPH1 is 1 of several enzymes involved in synthesis of diphthamide in EEF2 (Liu et al., 2004 [PubMed 15485916]).[supplied by OMIM
Specifications
Specifications
| Antigen | DPH1 |
| Applications | ELISA, Immunofluorescence, Western Blot |
| Classification | Monoclonal |
| Clone | 2C5 |
| Conjugate | Unconjugated |
| Description | Mouse monoclonal antibody raised against a partial recombinant DPH1. |
| Formulation | PBS with no preservative; pH 7.4 |
| Gene | DPH1 |
| Gene Accession No. | NM_001383 |
| Gene Alias | DPH2L/DPH2L1/FLJ33211/OVCA1 |
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