DSC2, Mouse, Clone: 1F2, Abnova™

Catalog No.	Quantity
89-021-356	100 μg

Catalog No. 89-021-356 Supplier Abnova Corporation Supplier No. H00001824M14

Description

Mouse monoclonal antibody raised against a partial recombinant DSC2.

The protein encoded by this gene is a calcium-dependent glycoprotein that is a member of the desmocollin subfamily of the cadherin superfamily. These desmosomal family members, along with the desmogleins, are found primarily in epithelial cells where they constitute the adhesive proteins of the desmosome cell-cell junction and are required for cell adhesion and desmosome formation. The desmosomal family members are arranged in two clusters on chromosome 18, occupying less than 650kb combined. Mutations in this gene are associated with arrhythmogenic right ventricular dysplasia-11. Alternative splicing results in two transcript variants encoding distinct isoforms. [provided by RefSeq

Sequence: SREASPRSAMSTATVTVNVEDQDEGPECNPPIQTVRMKENAEVGTTSNGYKAYDPETRSSSGIRYKKLTDPTGWVTIDENTGSIKVFRSLD

Specifications

• Antigen: DSC2
• Applications: ELISA, Western Blot
• Classification: Monoclonal
• Clone: 1F2
• Conjugate: Unconjugated
• Description: Mouse monoclonal antibody raised against a partial recombinant DSC2.
• Formulation: PBS with no preservative; pH 7.4
• Gene: DSC2
• Gene Accession No.: NM_024422
• Gene Alias: ARVD11/CDHF2/DG2/DGII/III/DKFZp686I11137/DSC3
• Gene Symbols: DSC2
• Host Species: Mouse
• Immunogen: DSC2 (NP_077740.1, 444 a.a. ∼ 534 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
• Purification Method: Affinity chromatography
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 1824
• Target Species: Human
• Content And Storage: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG2b κ