DUSP5, Mouse, Clone: 3D8, Abnova
Mouse monoclonal antibody raised against a partial recombinant DUSP5.
Manufacturer: Abnova Corporation H00001847M02A
The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates ERK1, is expressed in a variety of tissues with the highest levels in pancreas and brain, and is localized in the nucleus. [provided by RefSeqSequence: LKEAFDYIKQRRSMVSPNFGFMGQLLQYESEILPSTPNPQPPSCQGEAAGSSLIGHLQTLSPDMQGAYCTFPASVLAPVPTHSTVSELSRSPVATATSC
|dual specificity phosphatase 5|
|DUSP5 (NP_004410, 286 a.a. ∽385 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26kDa|
|Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.|
|In ascites fluid|
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