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DUSP5, Mouse, Clone: 3D8, Abnova™

Mouse monoclonal antibody raised against a partial recombinant DUSP5.

Manufacturer:  Abnova Corporation H00001847M02A

Catalog No. 89-021-371


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Specifications

Description

The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates ERK1, is expressed in a variety of tissues with the highest levels in pancreas and brain, and is localized in the nucleus. [provided by RefSeq

Sequence: LKEAFDYIKQRRSMVSPNFGFMGQLLQYESEILPSTPNPQPPSCQGEAAGSSLIGHLQTLSPDMQGAYCTFPASVLAPVPTHSTVSELSRSPVATATSC
Description & Specifications

Specifications

DUSP5
3D8
dual specificity phosphatase 5
DUSP5
Ascites
DUSP5
DUSP5 (NP_004410, 286 a.a. ∽385 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26kDa
200μL
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Monoclonal
Human
ELISA,Western Blot
Unlabeled
In ascites fluid
NM_004419
DUSP, HVH3
Murine
IgG1, κ
RUO
Primary
1847
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