Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More

Dystrobrevin Mouse, Unlabeled, Clone: 23, BD

Mouse Monoclonal Antibody

Manufacturer:  BD Biosciences 610766

Catalog No. BDB610766


Add to cart

Description

Description

Acetylcholine receptor clustering is considered an early event and a marker for synaptogenesis between a motor neuron and a muscle fiber. This process is mediated by the extracellular protein Agrin which binds to α; and β; Dystroglycan, previously discovered as Dystrobrevin- associated proteins. Dystrobrevin binds to the actin cytoskeleton by its N-terminal domain, thus providing the link between the actin cytoskeleton and receptor clustering. In Torpedo electric organ, Dystrobrevin is a prominent phosphotyrosine-containing protein. Murine Dystrobrevins comprise a family of four related proteins (1-4) with similar function, generated by alternative splicing. Dystrobrevin-1 is 688 amino acids and has an apparent mobility of 87kDa. Dystrobrevin-2 shares almost identical sequence with Dystrobrevin-1 in the first 500 amino acids and has an apparent mobility of 59kDa.
Specifications

Specifications

Dystrobrevin
23
Unconjugated
Affinity Purified
Mouse Dystrobrevin aa. 249-403
50μg
Cell Biology
Primary
Murine, Rabbit, Rat
Western Blot
250μg/mL
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Murine
IgG1
RUO
Store undiluted at -20°C.
Monoclonal
Documents
Provide Content Correction

We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Cancel Submit