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EBP50 Mouse anti-Human, Clone: EBP-10, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA119291

Catalog No. 01-676-047


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Description

Description

For use in Western blot applications, MA1-19291 should be placed in a vertical incubator for 60 minutes. A suggested positive control for this product is RAJI human lymphoma cell lysate.

NHERF1 (Na+/H+ exchanger regulatory factor 1), also known as EBP50 (ezrin, radixin, moesin-binding phosphoprotein 50) is an adaptor protein, which associates with beta-catenin and is required for its localization at the cell-cell junctions, interacts with various G protein-coupled receptors and regulates their traffic, as well as sodium-hydrogen exchange and sodium-dependent phosphate transport. NHERF1/EBP50 inhibits cell motility and is required to suppress anchorage-independent growth. It contains C-terminal ERM (ezrin, radixin, moesin)-binding region and two N-terminal PDZ (postsynaptic-density-95/disc-large/ZO1 homology) domains and is able to form head-to-tail intramolecular conformation to regulate its interactions.
Specifications

Specifications

EBP50
Monoclonal
1 mg/mL
PBS with 15mM sodium azide; pH 7.4
Q9JJ19, O14745
EBP50
Mouse
IgG2b
100 μg
4° C, do not freeze
Primary
59114, 9368
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
EBP-10
Unconjugated
SLC9A3R1
Liquid
SLC9A3R1
Bacterially produced, recombit, full-length human NHERF1.
Protein A
RUO
Antibody
Monoclonal
Human
Documents
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